Question: One gram of a drug was given to a patient by IV administration. Shortly after (following quick distribution and before any significant elimination has occurred),

One gram of a drug was given to a patient by IV administration. Shortly after (following quick distribution and before any significant elimination has occurred), its plasma concentration was found to be 0.6 mg/L. The half-life of the drug is 8hrs. The desired Steady State concentration is 1.2 mg/L. How frequently do we need to provide a repeating dose of 1g to reach this desired steady state?

(A) Every 2 hrs.

(B) Every 4hrs

(D) Every 16 hrs.

(E) Once a dayn

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