Evaluate the integral

${\displaystyle \underset{\phantom{}}{\overset{\phantom{}}{}}}(2x8)(x^{2}8x8{)}^{3}dx$

by making the substitution $u=x^{2}8x8.$

$C$

NOTE: Your answer should be in terms of $x$ and not $u.$

$$

$\frac{\frac{?}{?}}{?}$