Question: Explain in an easy way and function Regulating Interstitial fluid & plasma Osmolarity... (now beyond the kidney... osmolarity throughout the ENTIRE body!) . Osmolarity of

Explain in an easy way and function

Regulating Interstitial fluid & plasma Osmolarity... (now beyond the kidney... osmolarity throughout the ENTIRE body!) . Osmolarity of interstitial fluid & blood plasma is dependent on water content, w/ homeostasis requiring a balance between water loss & water gain... (i.e. assume salts constant, water variable) . ** *Impt: Blood Osmolarity is acutely regulated by water retention in the body (ADH) . VS. Blood Volume (& blood pressure) is long-term regulated by retention of 'salt' -> Na+ (RAAS & ANP)... & water follows this salt. Regulating Osmolarity Sensor cells for osmolarity are in the hypothalamus... ADH neurons (ADH is anti-diuretic hormone (aka. vasopressin) ) Effectors for osmolarity regulation -> the epithelial cells lining the collecting duct express ADH receptor . The hypothalamus cells release ADH which then increases permeability of the collecting duct to water

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