Question: Explain in an easy way and function The countercurrent multiplier in the Loop of Henle Now the Descending limb: salts stay in the tubular fluid

Explain in an easy way and function

The "countercurrent multiplier" in the Loop of Henle Now the Descending limb: salts stay in the tubular fluid (there are no Na+ pumps here), yet water in tubular fluid moves out- Why?... tubular water is chasing salt pumped out by ascending limb into the interstitial space. And then... Vasa Recta: the interstitial water from above enters the super Na+ salty blood coming from ascending side... this water is carried out of the medulla & whisked away back to the general circulation! Establishing the concentration gradient Result of the Descending Ascending limb limb Water out countercurrent multiplier... 300 mOsm - 100 mOsm Interstitial (in tubular fluid) Cortex fluid Tubular fluid Water out Medulla Blood (in vasa recta blood) Descending limb Ascending limb loses water and the loses salts and the tubular fluid becomes interstitial fluid becomes more concentrated. more concentrated. Salts Salts Loop of Salt in Salts Salt in salts Henle Water Vasa recta lose Vasa recta gain salts, gain water. Water salts, lose water. 1200 mOsm Salt in

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