Question: Explain in an easy way and function Unique properties of the ascending limb of the Loop of Henle: - Primary active transport (ATP Fluid Thick

Explain in an easy way and function

Unique properties of the ascending limb of the Loop of Henle: - Primary active transport (ATP Fluid Thick ascending Vasa recta driven pumps) of NaCl at in tubule limb cell lumen basolateral membrane- 'pumps' Nat out of filtrate ATP Nat ..... Nat ADP - Na+ enters interstitial space... Nat Na.. Nat 2CI 2CI . . . . . . . . . 2CI .. .. 2Cr can then enter blood in vasa K+ K Y. . . . . . .. recta at this location Cations: . . . . .. . . . . . . . . . . .... . . ...... Cations Na - * Water can't follow!!! ... the K Apical membrane Ca2+ (impermeable to water) Interstitial fluid is more Mo2+ apical/luminal membrane here is negative than fluid in tubule lumen impermeable to water. Key: Na*-K*-2CI symporter *Also note how K+ Leakage channels is lost as Nat is Sodium-potassium pump . . . Diffusion retained

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