For a future clinical trial with two treatment arms, the expected constant hazard ratio for the treatment
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Question:
For a future clinical trial with two treatment arms, the expected constant hazard ratio for the treatment group versus the control group is assumed to be 0.85.
A) If the known median survival time for the control group is 5 years, what should be the expected survival probability of the treatment group at 5 years?
B) How many patients do we need in the treatment group to see at least 25 deaths by 5 years with approx 95% probability?
C) What should be the range of the expected hazard ratio when the expected survival probability for the treatment group at 5 years is between 30% and 45%?
Related Book For
Fundamentals of Investments
ISBN: 978-0132926171
3rd edition
Authors: Gordon J. Alexander, William F. Sharpe, Jeffery V. Bailey
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