For the following potential mutations, put an

S$.$by those most likely to change the structure of the protein produced, put an $E$ by those most likely to affect the expression of the gene in question, and put an N by those expected to have neither of this effects. $(12$ pts$)$

base substitution in the promoter

deletion of the operator of the lac operon

silent mutation in a eukaryotic exon

nonsense mutation in a eukaryotic exon

base substitution in the $3^{\text{'}}$ UTR

deletion in the enhancer

base substitution in the Shine Dalgarno sequence

deletion of the TATA box.

missense mutation in a eukaryotic exon

$3$ bp insertion in a eukaryotic exon

$2$ bp insertion in a eukaryotic intron

$2$ bp insertion in a eukaryotic exon