Question: Fully grown mice may be generated using embryonic stem cells in which Homologous recombination replaced the targeted endogenous gene with part of the targeting vector.

Fully grown mice may be generated using embryonic stem cells in which Homologous recombination replaced the targeted endogenous gene with part of the targeting vector. These so called founder mice, which are males, are bred with wild type females to generate null mutant mouse lines. Please describe the possible genotypes of the offspring born from the ( founder male) x (wild female) cross

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