G12 10 Sample size requirement A variable has a standard deviation of 40 mg dL We want to test a mean difference in two groups with alpha 0 05 (two sided) and power 80 How many observations are needed to detect a difference of 10 mg dL with equally sized groups Suppose we can only recruit 150 subjects into group 1 How many are needed in group 2

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Question: G12.10 Sample size requirement. A variable has a standard deviation of 40 mg/dL. We want to test a mean difference in two groups with alpha=0.05

G12.10

Sample size requirement.A variable has a standard deviation of 40 mg/dL. We want to test a mean difference in two groups with alpha=0.05 (two-sided) and power=80%.

How many observations are needed to detect a difference of 10 mg/dL with equally sized groups?

Suppose we can only recruit 150 subjects into group 1. How many are needed in group 2?

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