help me answer the following in a paragraph format: Looking at research on gain-of-function (GOF) studies, especially those utilizing the H5N1 influenza virus, raises some difficult questions about how to strike a balance between public safety and scientific progress as a whole. Examining the referenced material makes it clear that, even while such study may lead to better knowledge of viral mechanics and increased readiness for future pandemics, there are risks involved that should not be disregarded. For instance, Osterholm and Relman's discussion of the development of a mammalian-transmissible H5N1 strain represents a major advancement in our knowledge of influenza transmissibility, but it also presents valid questions about biosecurity and the possibility of unintentional release or abuse. As outlined in one article, there are significant concerns about global biosecurity, biosafety, and public health as well as severe problems about scientific censorship raised by two recently submitted publications to Science and Nature. These two papers detail the successful production of H5N1 influenza mutant isolates. a virus that ferrets can contract through their respiratory systems (Osterholm & Kelley, 2013). Many believe that the need to protect public health serves as the foundation for the rationale for this research. GOF research must be guided by thorough risk and benefit analyses, as specified in the NSABB's framework. Including a seven step risk analysis and five step benefit analysis (NSABB, 2015). Risk Categories include: Biosafety Physical and personnel security Pro