Question: help me please 17 Fill in the Blank 1 point SOS acts as a GEF RAS activates RAF (very complicated leading to phosphorylation) RAF is

help me please

help me please 17 Fill in the Blank 1 point SOS
17 Fill in the Blank 1 point SOS acts as a GEF RAS activates RAF (very complicated leading to phosphorylation) RAF is a MEK kinase. MEK is an ERK kinase ERK turns on the transcription factors If MEK couldn't phosphorylate ERK what would be a consequence? Over proliferation of cells choose your answer... No cell division choose your answer... RAS would stay bound to GTP choose your answer... MEK wouldn't transfer its phosphate to ERK choose your answer... choose your answer... R overexpression: this is not how kinases work lorectal cancer (27-77%) ncreatic cancer (30-50%) not a consequence g cancer (40-80%) h-small cell lung cancer (14-91%) a consequence 19030303 Ras Sos Ras mutation: EGFR' . Pancreatic cancer (90%) IT- Grb2 . Papillary thyroid cancer (60%) Raf* . Colon cancer (50%) . Non-small cell lung cancer (30%) + EGFR mutation: B-Raf mutation: . NSCLC (10%) . Melanoma (70%) . Glioblastoma (20%) MEK . Papillary thyroid cancer (50%) . Colon cancer (10%) ERK OO *Mutated in human cancers

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