Question: Hi hi , a cell bio question ( undergrad ) . do primers start specifically at start codons in DNA replication, or are they randomly
Hi hi a cell bio question undergrad
do primers start specifically at start codons in DNA replication, or are they randomly placed?
like, we know primase forms primers specifically at start codons during rna translation for protein synthesis i think But do they do the same for DNA? During replication? i dunno, since the goal isnt really to copy a specific gene, per se but the entire genome. So would it be just at a random location the Rna primase places the primer, for DNA polymerase to begin? I suppose it would, right? Since well, replication origins are random and bidirectional.
This is regarding the leading strand. pretty sure we know that the lagging strand will have it's primers usually placed as close to the replication fork as possible, since that is where it last left off during the synthesis of the new strand, as it goes in that antiparallel direction.
ykwim?
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