i need a one paragraph response to this with one reference not older than five years.

While statisticalsignificanceand clinical significance arekeyterms in clinical research, these terms significantly differ.Statistical significance does not always imply clinical significanceasthe results may be too small to make any meaningful impact in clinical settings (Willigenburg & Poolman, 2023).Statistical significance indicates the reliability of the study resultswhileclinical significance reflects itsimpact onclinical practices.

Statistical significance indicates that the results of a study are likely to be attributable to a specific cause and not chance alone (Sharma, 2021). Statistical significanceis determinedby using statistical tests such as t-tests and ANOVA in which alevel of significanceis set. For instance, a researcher can set alevel ofsignificanceat 95 %( a=0.05). If the associated p-value of a test is lower than the set significance level, the results are considered statistically significant. On the other hand, clinical significance indicates where the results are large enough to make a meaningful impact in clinical practice. Clinicalsignificanceis often assessed based onfactors such aseffect size and clinical judgment.