If someone could solve it in excel please

In the batch extraction of an enzyme from S$.$ Cerevisiae, a high $-$ speed $4$L capacity bead mill was used.

a$)$ Calculate the kinetic release constants of proteins $($R$)$ and enzyme $($A$)$

b$)$ Establish the times at wich $80\%$ and $90\%$ of the enzyme are released, as well as the specific activity at the moment

c$)$ Estimate the fraction of empty volume of the chamber when the load of the pearl is $80\%$