If the population of students at CSU is approximately 35,000, and we know that PKU would...
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If the population of students at CSU is approximately 35,000, and we know that PKU would occur at the rate of 6 per 100,000 births in this population, what is the frequency of the PKU alleles in the population? [3 points] [Hint: treat all of the possible mutant alleles as binned into one allele category]. How many carriers (heterozygotes) are expected in the population of CSU students? [2 points] If we assume an equal sex ratio and random matting among PAH genotypes, what is the probability that different pairs of mates will have a PKU child? [4 points] [Hint: this population is large enough that you can assume allele and genotype frequencies will behave as expected in an infinite population] If we wanted to do this study for ALL segregating PAH alleles and genotypes, what additional data would we need? [1 point] If the population of students at CSU is approximately 35,000, and we know that PKU would occur at the rate of 6 per 100,000 births in this population, what is the frequency of the PKU alleles in the population? [3 points] [Hint: treat all of the possible mutant alleles as binned into one allele category]. How many carriers (heterozygotes) are expected in the population of CSU students? [2 points] If we assume an equal sex ratio and random matting among PAH genotypes, what is the probability that different pairs of mates will have a PKU child? [4 points] [Hint: this population is large enough that you can assume allele and genotype frequencies will behave as expected in an infinite population] If we wanted to do this study for ALL segregating PAH alleles and genotypes, what additional data would we need? [1 point]
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Related Book For
Mathematical Applications for the Management Life and Social Sciences
ISBN: 978-1305108042
11th edition
Authors: Ronald J. Harshbarger, James J. Reynolds
Posted Date:
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