If your sample material is large and difficult to work with as a whole (e.g. leaf, muscle tissue), which of these 3 methods will be the best option in order to optimise your sample preparation prior to nucleic acid extraction in the quickest possible time? Motivate for your choice.
a)Cut it up into smaller pieces and use those.
b) Use some form of mechanical tissue lyser.
c) Soak it in formaldehyde prior to starting the extraction.