In Chymotrypsin, a mutant was constructed with Ser189, which is in the bottom of the substrate specificity

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In Chymotrypsin, a mutant was constructed with Ser189, which is in the bottom of the substrate specificity pocket, changed to Asp. What effect would you predict for the Ser189 to Asp189 mutation.

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Organic Chemistry A Short Course

ISBN: 978-1111425562

13th edition

Authors: Harold Hart, Christopher M. Hadad, Leslie E. Craine, David J. Hart

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Posted Date: Nov 28, 2019 01:34 AM

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In Chymotrypsin, a mutant was constructed with Ser189, which is in the bottom of the substrate specificity

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Chymotrypsin is site specific protease and will only cleave the carboxyl side of large hydropho... View the full answer

Organic Chemistry A Short Course

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