Lab 6: Rate Standardization Part A. Direct Adjustment: Multiple Sclerosis in 3 US communities. World and US Age Distributions from 2000 that were used in the Noonan article are provided below. These data are from Klein and Schoenborn, 2001 and Zivadinov et al., 2003. Link to Noonan Article (for Lorain County, Ohio information): http://www.cdc.gov/pcd/issues/2010/Jan/08_0241.htm Age (years) <30 30-39 40-49 50-59 60-69>=70 Total US Standard Population (2000) 114,763 41,691 42,285 30,531 20,064 25,300 274,634 US Population Proportion (2000) 0.42 0.15 0.15 0.11 0.07 0.09 1.0 World Standard Population Proportion (2000) 0.56 0.12 0.12 0.09 0.07 0.04 1.0 1. (a) Using the age-specific rates for Lorain County, Ohio and both the US and world population data from above, apply direct standardization to compute the US and world age-adjusted rates for this region. Age <30 30-39 40-49 50-59 60-69>=70 Total Rate in Lorein 8.60 80.03 212.43 306.55 189.68 142.86 112.41 US std 3.59 12.15 32.71 34.08 13.86 13.16 109.55 world std 4.82 9.60 25.49 27.59 13.28 5.71 86.49 Page 1 of 7 Revised 2/27/13 (b) Compare your results from (a) with the results shown on page 8 of the article. Results are the same in my calculations and table. 2. Why do you think the authors did not adjust for sex in the data presented in the Table (i.e., page 8)? It is possible that the author was interested of bringing awareness to the overall population regardless of the sex and that is why they did not use it. However, it is evident that it is more prevalent in females and sex standardization would have been more reliable to truly compared among states. 3. Why do the US age-adjusted and world age-adjusted rates differ? Because proportions are different in each region. It is more prevalent in the world for people <3013