lets work on this problem 19 Growth factor receptors on the cell surface, such as EGF R, receive signals that promote cell growth and division To limit this signaling pathway, EGF R is removed from the cell surface through endocytosis, followed by degradation by the lysosome Which of the following describes the best experiment to test if EGF R enters the cell through the clathrin dependent endocytic pathway Note EGF epidermal growth factor, EGF R receptor for EGF a Knockout EGF R and test effects on EGF R signaling b Prevent lysosomal acidification and measure EGF R signaling c Prevent endosomal acidification and measure EGF R signaling d Disrupt the function of the AP 2 adaptor and measure EGF R signaling e Disrupt the function of the AP 2 adaptor and measure the localization of EGF R

Question

lets work on this problem 19  Growth factor receptors on the cell surface, such as EGF R, receive signals that promote cell growth and division  To limit this signaling pathway, EGF R is removed from the cell surface through endocytosis, followed by degradation by the lysosome  Which of the following describes the best experiment to test if EGF R enters the cell through the clathrin dependent endocytic pathway  Note  EGF  epidermal growth factor, EGF R  receptor for EGF a  Knockout EGF R and test effects on EGF R signaling b  Prevent lysosomal acidification and measure EGF R signaling c  Prevent endosomal acidification and measure EGF R signaling d  Disrupt the function of the AP 2 adaptor and measure EGF R signaling e  Disrupt the function of the AP 2 adaptor and measure the localization of EGF R

SolutionInn · Accepted Answer

The Answer is in the image, click to view ...

Question: lets work on this problem 19. Growth factor receptors on the cell surface, such as EGF-R, receive signals that promote cell growth and division. To

Step by Step Solution