Microsoft Word - PHP 405 Problem Set 1.docx

Since 1948, the Framingham Study has followed 2,336 males and 2,873 females in order to investigate the relationship between risk factors and the development of cardiovascular disease. Data from the Framingham Study on serum cholesterol levels and coronary heart disease in men and women are show in the table below. Calculate the values for boxes labeled A through N in this table. Use the lowest level of serum cholesterol as the reference category for calculation of relative risk and risk differences.

Table: Cumulative Incidence of CHD by serum cholesterol at baseline, Ages 40-59, Framingham Study.

Serum Cholesterol (mg/100 mL)	New CHD Cases	Population at Risk	Cumulative Incidence (per 1000)	Relative Risk	Risk Difference (per 1000)
Men
<210	16	454	A	1 (Reference)	0 (Reference)
210-244	29	455	B	G	K
>245	51	424	C	H	L
Women
<210	8	445	D	1 (Reference)	0 (Reference)
210-244	16	527	E	I	M
>245	30	689	F	J	N