Question: Need help on the sketch, the potentials, and the bottom question A cell is being studied in a whole cell patch clamp experiment and is
A cell is being studied in a whole cell patch clamp experiment and is perfused with a solution of 100 mM KCl at a temperature of 25 C. The external solution contains 1 mM KCI plus impermeable molecules to adjust osmolarity and pH. Sketch the experimental cell noting ion concentrations inside and outside. Calculate the equilibrium potential (Erev) for K and Ch. The current-voltage curve below was obtained during a fast voltage ramp from-100 mV to 50 mv. Assuming the ramp was fast enough to prevent channel activation or inactivation, is the resting membrane more permeable to potassium or chloride? Explain. + 25 + 50 -50 -25 A cell is being studied in a whole cell patch clamp experiment and is perfused with a solution of 100 mM KCl at a temperature of 25 C. The external solution contains 1 mM KCI plus impermeable molecules to adjust osmolarity and pH. Sketch the experimental cell noting ion concentrations inside and outside. Calculate the equilibrium potential (Erev) for K and Ch. The current-voltage curve below was obtained during a fast voltage ramp from-100 mV to 50 mv. Assuming the ramp was fast enough to prevent channel activation or inactivation, is the resting membrane more permeable to potassium or chloride? Explain. + 25 + 50 -50 -25
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