Please answer Q2&3

2. What does this exercise have to say about the relationship between sample size and statistical significance? Be very specific in your answer. 3. What does this exercise have to say about whether one can reliably infer practical significance from statistical significance?The N Crowd An MD/Ph.D at a major research institution is studying a new cannabis-based pain medication. The patients who volunteer for the study are randomly divided into two groups. Group 1 is given a placebo (Treatment 1). After one hour, group members rate the effectiveness of the pain relief on a scale of 1 to 100. Group 2 is given the new drug (Treatment 2), then group members rate the pain relief effectiveness in a similar way. Initially, only 25 volunteers were available for each group. By the end of the month, however, there were 25,000 volunteers in each group, making this the largest clinical trial in recent memory. Amazingly, there is only a one-point difference between the ratings of the placebo group and the ratings of the active treatment group at each stage. Formally, the following choice has to be made: H: Treatment 2 is no different than Treatment 1 H : Treatment 2 is more effective than Treatment 1 TABLE 5.1 Statistically Significant Results 1st 2nd 3rd 4th Week Week Week Week Sample size in each group (N) 25 250 2,500 25,000 Standard deviation 20 20 20 20 in each group Treatment 1 mean (placebo] 50 50 50 50 Treatment 2 mean 51 51 51 (new drug) 51 p-value 0.430 Statistically significant? Yes Yes O Yes O Yes Check 'Yes' or "No' No O No No O No