Question: please explain the answers, thanksss. INTERACTIONS/SOLUBILITY CASE K. presents a prescription for her 6-month-old daughter for Donatussin Drops. She wants to know if this medication

 please explain the answers, thanksss. INTERACTIONS/SOLUBILITY CASE K. presents a prescription

please explain the answers, thanksss.

INTERACTIONS/SOLUBILITY CASE K. presents a prescription for her 6-month-old daughter for Donatussin Drops. She wants to know if this medication will have an effect on her daughter's alertness Components of Daniatussin: Phenylephrine (decongestant) Chlorpheniramine (antihistamine) Guaifenesin (expectorant) HO OH NHCH CH CHE Phenylephrine CH Chiarpheniramine OCH Guaifenesin 1. Identify the structural features/functional groups of phenyl ephrine and guaifenesin that contribute to improved water solubility (medication given as drops). List the types of interactions that these groups have with water and draw an example of these interactions with appropriate labels). 2. Evaluate each of the three molecules, and determine if each molecule contains any functional groups that will allow the drug to cross the blood-brain barrier and have an effect on this child's alertness (create a list of relevant func tional groups for each molecule). Based on your evaluation, which agent is likely to have the most significant effect? Identify what property is necessary for these agents to cross this biologic membrane 3. Identify the binding interactions that chlorpheniramine and guaifenesin could have with their respective targets for drug action Be sure to identify which functional groups will participate in each of these binding interactions

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