Please help me, in manual computation show how you solve it

1. In an experiment conducted in the civil Engineering Department at Virgina Tech, growth of a certain type of algae in water was observed as a function of time and the dosage of copper added to the water. The data are as follows: Response is in units of algae. (Use first method). 0.05 level of significance. Time in days Copper 5 12 18 0.30 0.37 0.25 1 0.34 0.36 0.23 0.32 0.35 0.4 0.24 0.30 0.27 2 0.23 0.32 0.25 0.22 0.31 0.25 a. Fit the model: y = Bot B1X1+ B2x2 + B12*1*2+ Blix? + Bzzx2+ &; b. Do an analysis of variance C. Comment concerning whether the data are sufficient to show a time effect on algae concentration. d. Do the same for copper content. Des the level of copper impact algae concertation e. Comment on the results of the test for interaction. How is the effect of copper content influenced by time? 2. Three strains of rats were studied under 2 environmental conditions for their performance in a maze test. The error scores for the 48 rats were recorded. Strain Environment Bright Mixed Dull 28 12 33 83 101 94 22 23 36 14 33 56 Free 25 10 41 76 122 83 36 86 22 58 35 23 72 32 60 89 136 120 48 93 35 126 38 153 Restricted 25 31 83 110 64 128 91 19 99 118 87 140 (use first method).Use a 0.01 level of significance to test the hypothesis that a. There is no difference in error scores for different environments b. There is no difference in error scores for different strains c. The environment and the strains of rat do not interact