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Question 4 (Total: 15 marks) A chromatography column has 40mm internal diameter and is 10cm long. The column is filled with a matrix of 200m particle radius and has a voidage of 0.3. You want to pass though the column a solution that has the fluid properties of water. Additional column diameters have been tested to determine the corresponding critical velocity using the same matrix and solution (Table 3.1). Table 4.1. Pressure drop in different column diameters. a) Determine the pressure drop of the 40mm (ID) column if you operate at the column at the critical velocity. [20 marks] b) If you double the matrix particle diameter, by how much would the pressure drop change