Please write and post a Matlab code solving this problem.

Treatment of familial adenomatous polyposis Formation of adenomatous polyps in the colon is often followed by development of colon cancer. Non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin, are cyclooxygenase (cox) inhibitors and have been linked in multiple studies to regression of colorectal adenomas and a lowering of colon cancer incidence. Mutation of the adenomatous polyposis coli (APC) gene predisposes a person to colon adenoma. Those who inherit the mutated APC gene develop familial adenomatous polyps and are at greater risk for developing colon cancer. In a randomized, double-blinded study (Steinbach et al., 2000), a cox-2 inhibitor called celecoxib was administered to patients who had developed familial adenomatous polyps. Placebo was given to another group of patients as a control case. The percent changes from baseline after 6 months of treatment in the number of colorectal polyps in patients treated with celecoxib twice per day and with placebo are listed below Placebo (n = 15) 20, 17, 14, 0, 0, 0, 0, 0, -2, -8, -10, -13, -17, -20, -45 400 mg of celecoxib administered 2 times daily (n = 30) 20, 4, 0, 0, 0, 0, 0, -10, -14, -16, -16.5, -18, -19, -19.5, -28.5, -30, -30.5, -38, -38 -40, -40, -43, -45, -47, -50, -52, -55, -58, -70, -80. Using a non-parametric method, test the hypothesis that celecoxib reduces the occurrence of adenomatous polyps in patients with familial adenomatous polyposis. What assumptions are necessary to apply the appropriate hypothesis test