Question: Potential near a protein. Adapted from Problem 9 . 8 Physical Biology of the cell, Phillips et al . Consider a protein sphere with a

Potential near a protein. Adapted from Problem 9.8 Physical Biology of the cell, Phillips et al.
Consider a protein sphere with a radius of 1.8nm, and charge Q =10e, in an aqueous solution of c =0.05M NaCl at 250C. Consider the small ions as point charges and use the linear approximation to the PoissonBoltzmann equation.
(a) Derive an expression for the potential V (r) of a charge sphere in a salty solution. Assume that the electrical potential at distance r from the center of a charged sphere is:
Ar
V(r)= eD (1)
r where A is constant and D the Debye length.
Determine the constant A by computing the electric field from the potential and set it equal to E(R)= Q
4R2
(b) What is the surface potential of the protein in units kBT/e?
(c) What is the concentration of Na+ions and of Cl ions at the surface of the protein?

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