Problem 10 Determine whether the study is an experiment or an observational study, and then identify a major problem with the study. The Physicians' Health Study involved 22,071 male physicians. Based on random selections, 11,037 of them were treated with aspirin and the other 11,034 were given placebos. The study was stopped early because it became clear that aspirin reduced the risk of myocardial infarctions by a substantial amount. This is an (1). because the researchers (2) the individuals. What is a major problem with the study? A. The results apply only to male physicians. OB. There is no blinding or replication, which has a high chance of leading to bias. C. The results apply only to individuals with heart disease. D. This is a convenience sample with voluntary response, which has a high chance of leading to bias. (1) O experiment observational study (2) do not attempt to modify apply a treatment to