Problem 4 9 points total a (4 points) As a trial treatment, a custom amino acid with two methyl groups at the alpha carbon (2 methylalanine) is synthesized and polymerized into a polypeptide This amino acid derivative is given the label O and is estimated to have 7 backbone rotational conformations What is the entropic cost of locking this amino acid into 1 conformation b (5 points) Would replacing Ala residues with O residues in proteins cause an increase or decrease in stability of the protein Justify your

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Problem 4  9 points total a  (4 points) As a trial treatment, a custom amino acid with two methyl groups at the alpha carbon (2  methylalanine) is synthesized and polymerized into a polypeptide  This amino acid derivative is given the label   O   and is estimated to have 7 backbone rotational conformations  What is the entropic cost of locking this amino acid into 1 conformation  b  (5 points) Would replacing Ala residues with   O   residues in proteins cause an increase or decrease in stability of the protein  Justify your

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Question: Problem 4: 9 points total a. (4 points) As a trial treatment, a custom amino acid with two methyl groups at the alpha carbon (2-

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