Question: Problem 4 . Radioactive isotopes play an important role in Medicine for radiation therapy and medical imaging. Solutions with radioactive isotopes lose quickly use their

Problem 4.
Radioactive isotopes play an important role in Medicine for radiation therapy and medical imaging.
Solutions with radioactive isotopes lose quickly use their "potency" due to the radioactive decay.
It is therefore often necessary to isolate radioactive isotopes (produced in a synchrotron or nuclear
reactor) from their decay products immediately before its medical use. The efficiency of this
purification process may be increased through a recycling process. In a good approximation the
decay of a radioactive isotope can be treated in analogy to chemical reactions.
A diagnostic medical procedure is based on the detection of the decay of a radioactive isotope A.
Isotope A decays to another isotope B via a radioactive decay:
AB
This process occurs with a time constant k=0.05min-1 according to
nA=nA,0exp(-kt)
A mixture of A and B is isolated from a nuclear production process. The medical procedure
requires the pure isotope A. Therefore, A and B are undergoing a continuous separation process
at the site of the medical procedure. We are analyzing this separation step:
Consider a constant feed of an aqueous solution of 100ml? hour containing 10mg of isotope A
and 50mg of isotope B. This isotope mixture enters a chromatographic separation process. It
takes 20 minutes for the feed to pass through this separator. Two streams exit the column. The
desired stream contains an aqueous solution of pure A leaving the reactor with a rate of
1mg? hour. The remaining stream contains components A and B. It is split in two equal parts
such that 50% of this stream is recycled, the other 50% are discarded as nuclear waste. All flows
associated with the recycling process are sufficiently fast such that you may ignore nuclear
decays. However, you may not ignore any decay processes during the separation process.
Calculate the concentration of component A and B in all streams.
Hints: As stated above the nuclear decay can be treated in very good approximation as chemical
reaction, use equation (i) to calculate the conversion occurring in the separator. (2) In a very
good approximation the molecular weights of A and B can be considered identical.
 Problem 4. Radioactive isotopes play an important role in Medicine for

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