Provide a concept map exploring the four agonists on the agonist spectrum (agonist, partial agonist, antagonist, and inverse agonist) in which you:

• Describe the different characteristics of the four agonists and how each mediates distinct biological activities. Include proposed mechanisms and the receptor it is targeting.
• Identify how the P450 enzyme system plays a role in the body's absorption, distribution, and clearance of medication.
• Scavenge the literature after describing each agonist on the spectrum for research that is based on the medications in the table below.
• Apply the medications to the appropriate agonist on the agonist spectrum in your Concept Map.

Oxycodone, Brexpiprazole, Haloperidol, Naloxone, Aripiprazole, Amphetamine, isperidone, Pimavanserin

Provide Necessary References within