Question: Q1. Please explain why we care more about additive interaction than multiplicative interaction if what we are truly interested in evaluating is biologic interaction. In

Q1. Please explain why we care more about additive interaction than multiplicative interaction if what we are truly interested in evaluating is biologic interaction.

In your answer, please briefly address how this was shown using Rothman's logic to determine which scale matters.

Q2. More generally, is it true that non-differential misclassification of exposure will always bias towards the null?

Please explain.

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