Question $4(2$ points$)$

Predict the phenotype of E$.$ coli with the following $($partial diploid$)$ genotype at the lac operon:

lacI$+$lacP$+$lacO$+$lacZ$-$lacY$+1$

lacI$+$lacP$+lac{O}^c$lacZ$+$lacY$-$

$-$galactosidase active when external lactose is absent

permease active when external lactose is absent

$-$galactosidase active when external lactose is present

permease active when external lactose is present