Question $4$

A $46-$year$-$old man is currently enrolled in a Phase $2$ study of a drug for severe diabetic neuropathy. While the study is on$-$going a new drug becomes commercially available that may have equal or greater benefit to the subject. The investigator should do which of the following?

Gwe the subject comprehenalve information about the new drug induding its slide effects. Discuss the pros and cons of both the invertyational drug and the commerclatly awalthile drug and then clow the sub;wat to chacke whether to whatraw from the research to take the new drug.

Writhold this new Information to aveld confusing the wheipct with ocher treatomerit eptions or chiernatives.

$$ Do not tell the subject about the new drug because phyldins have the frith to try out new treatments with their patients.

$$ Tc: the subject about the new drug but discourage him from sumters treatments uniti the study is completed.