Regulation of gene expression can occur after transcription. a) Agene is alternatively spliced, such that exon...

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Regulation of gene expression can occur after transcription. a) Agene is alternatively spliced, such that exon 2 is included in skin cells and skipped in all other cell types. What molecular mechanism would a skin-specific protein use to allow exon 2 inclusion? b) In another gene, the 5'UTR of the MRNA has a stem-loop structure that is bound by protein A when intracellular iron is high. How does this structure likely affect gene expression? Regulation of gene expression can occur after transcription. a) Agene is alternatively spliced, such that exon 2 is included in skin cells and skipped in all other cell types. What molecular mechanism would a skin-specific protein use to allow exon 2 inclusion? b) In another gene, the 5'UTR of the MRNA has a stem-loop structure that is bound by protein A when intracellular iron is high. How does this structure likely affect gene expression?

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A Spliceswitching oligonucleotides SSOs control alternative splicing Diagram depicts premRNA transcr... View the full answer