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chemistry
august 2022
04

Chemistry Questions and Answers August 04, 2022

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For the following acid-catalyzed tandem Friedel-Crafts alkylation/cyclization reaction, please: 1) Draw the disconnection (for retrosynthesis) of the product to get the appropriate synthons 2) Draw the arrow-pushing mechanism for each step of the reaction to produce the given product 2) State the type of cyclization that occurs according to
$( frac{mathrm{CF}_{3} mathrm{CO}_{2} mathrm{H}(20 % mathrm{~mol})}{mathrm{DCE}, 80^{circ} mathrm{C}} )$

LOH CF3COH (20 mol) DCE, 80 C NH
$( frac{mathrm{CF}_{3} mathrm{CO}_{2} mathrm{H}(20 % mathrm{~mol})}{mathrm{DCE}, 80^{circ} mathrm{C}} )$

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