Select the best answer A. Randomized controlled trials are considered the \"gold standard\" of epidemiology study designs because randomization guarantees comparability of study arms. B. A weakness of randomized controlled trials is that they are prone to misclassification of exposure status. C. It is difficult to perform intention-to-treat analyses with randomized controlled trials. D. Randomized controlled trials are observation studies because study arms are observed for outcomes. E. Randomized controlled trials are not an effective study design for assessing rare outcomes