Question: Silicone implants are being explored as meniscal replacements. Experience has shown that the silicone membrane used in these implants can leak the silicone fluid within

Silicone implants are being explored as meniscal replacements. Experience has shown that\ the silicone membrane used in these implants can leak the silicone fluid within the\ surrounding tissue.\ Assume that the leakage is entirely by diffusion rather than by macroscopic pores.\ Assume the silicone oil has a molecular weight of 740 Dalton.\ Assume the membrane is 5 mm thick and the surface area is 400 cm2\ . The membrane has a\ diffusion constant of D = 1.2 x 10-17 cm2\ /sec.\ Assume that the implant has a volume of 500 cm3and a density of \\\ ho = 1.2 g/ cm3\ .\ i. Calculate the amount of leakage in a year (mol/year). You can assume that\ diffusion is governed by Fick's first law:\ where D is the diffusion coefficient, c is the concentration, and x is the\ (diffusion) distance. The flux is in units of mass per unit area per time. Assume\ the concentration in the tissue is initially zero.\ (10)\ ii. If only 1.2 x 10-10 ???\ ????\ leakage is tolerable at this particular implantation site,\ what is the maximum possible surface area of the implant?

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer
Step: 1 Unlock blur-text-image
Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock
Step: 3 Unlock

Students Have Also Explored These Related Civil Engineering Questions!