Simplify and cut this paragraph down: Learning about the history of research ethics significantly shaped my understanding and perspective on biomedical research. This historical context sheds light on the evolution of ethical standards and the importance of maintaining human rights in research. First, studying historical cases, such as the Tuskegee Syphilis Study and the unethical experiments during World War ll, highlights the potential abuse in biomedical research. These events serve as reminders of the consequences that can arise when ethical standards are not adhered to. Knowing and acknowledging these events fosters a deeper awareness of the necessity for regulatory framework to protect research participants. Furthermore, the establishment of guidelines like the Nuremberg Code and the Declaration of Helsinki reflect society's response to past ethical issues. These documents have laid the groundwork for ethical principles such as informed consent, the right to withdraw, and the assessment of risks versus benefits. Learning about these guidelines emphasizes the importance of safeguarding the dignity and rights of research participants in biomedical studies. As a future Nurse Practitioner who may partake in research, I am thankful to see the ethical progress and participant protection that has come to be. In addition, the evolution of IRBs as a requirement for conducting research is rooted in the historical lessons learned about oversight