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ecombinant plasmid.) asDNA = double-stranded DNA. in that only a small pe growth challenges, multiply, and produce numerous copies of the plasmid. If the plasmid vector provides antibiotic resistance, the expo bacteria will grow in the presence of antibiotics, thus selecting for cells containing the hybrid plasmids (Fig. 34.6). Artificial plasmids with are routinely constructed. An example is the classic pBR322 (see Fig. 34.5), which contains an origin of replication, two antibiotic Plas resistance genes, and 40 unique restriction sites. Use of plas mids is limited by the size of the DNA that can be inserted. tors that can