Table below refers to a study that investigated the relationship between smoking and myorcadial infarction (MI). The first column refers to 262 young and middle-aged women admitted to coronary units with acute MI during a 5-year period. Each case was matched with two control patients admitted to the same hospital with acute disorders. All subjects were classified according to whether they had ever been smokers.

Ever SmokerMI Cases Controls

No 98 260

Yes 202 340

Use Chi-square test to determine whether at 5% significance level proportional of smokers and non-smokers who suffer from MI are different.

(a) Calculate the test statistic.

(b)Calculate the p-value.

(c)Calculate the critical value.

(d) The decision is to reject the null hypothesis. True/False

Use Fisher's exact test to determine whether at 1% significance level proportional of smokers and non-smokers who suffer from MI are different.

(a) Calculate the p-value

(b)Calculate the lower bound of the 99% confidence interval of the odds ratio

(c)Calculate the upper bound of the 99% confidence interval of the odds ratio

(d) The decision is to reject the null hypothesis. True/False