Question: The figure below has been reproduced from a 2 0 0 7 study conducted by researchers from University of Schleswig - Holstein ( Germany )

The figure below has been reproduced from a 2007 study conducted by researchers from University of Schleswig-Holstein (Germany) and shows the resting membrane potential (RMP) of the atrium (A) and ventricle ( V ) of the heart of mice during early (ED) and late (LD) development. As you can see, there was a significant difference in RMP between ED and LD in both the atrium and ventricle, which the researchers showed could be entirely explained by differences in the activity of the sodium-calcium exchanger (NCX). Given that NCX exchanges three Na+ ions for every one Ca2+ ion, in which direction must the NCX operate during development in mouse hearts?
forward (i.e., Na+ in, Ca2+ out)
reverse (i.e.,Na+ out, Ca2+ in)
The figure below has been reproduced from a 2 0 0

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