In the table below (Table 1), 3 different spherical polymeric compounds at certain time intervals The experimentally
Question:
In the table below (Table 1), 3 different spherical polymeric compounds at certain time intervals
The experimentally measured cumulative effect of the drug (X) released from the particle (A, B, C)
concentration values are given. Pre-release polymeric particles of drug X
Their concentration in (Qo) is known as 13.476 mg/L.
a) Plot cumulative (mg/L) release graphs versus time
b) Depending on the experimental data in Table 1, all polymeric compounds of drugs
Evaluate the release mechanisms in particles by studying the Korsmeyer-Peppas, Higuchi and HixsonCrowell kinetic models
c) Determine the drug release kinetics of X for each delivery particle depending on the models.
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Table1. Time-dependent X drug concentration values (Qt)
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Managerial Accounting
ISBN: 978-1118385388
2nd edition
Authors: Ramji Balakrishnan, Konduru Sivaramakrishnan, Geoff B. Sprinkle