Question: The main disadvantage of introducing constraints into a linear program that enforce some or all of the decision variables to be either integer or binary

The main disadvantage of introducing constraints into a linear program that enforce some or all of the decision variables to be either integer or binary is that:
the constraints are difficult to formulate.
we cannot have "yes-or-no" decisions in the linear program.
the solutions will no longer be optimal.
the programs may take longer to solve.
Excel can no longer be used to solve the program.

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