Question: The Needleman- Wunsch method for aligning DNA sequences assigns 1 point whenever a mismatch occurs, and 3 points whenever a gap insertion or deletion) appears

The Needleman- Wunsch method for aligning DNA

The Needleman- Wunsch method for aligning DNA sequences assigns 1 point whenever a mismatch occurs, and 3 points whenever a gap insertion or deletion) appears in a sequence. Assume that under certain conditions, the number of mismatches has mean 5 and standard deviation of 2, and the number of gaps has mean 2 and standard deviation 1. If the number is independent, then the variance of the Needleman-Wunsch Score is 13, and the variance of the Needleman- Wunsch Score is 3.6055. If the number gaps are dependent on the number of mismatches, would the variance (or standard deviation of the Needleman-Wunsch score) be the same as you calculated in part 2) and 3)? Explain why

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer
Step: 1 Unlock blur-text-image
Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock
Step: 3 Unlock

Students Have Also Explored These Related General Management Questions!