The pk parameters for a drug given intravenously were described in the equation: D B = 1000

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Question:

The pk parameters for a drug given intravenously were described in the equation: D_B = 1000 e^{-0.17 t} (amount in mg, time in hour) and plasma concentration after 6 hours was found to be 14.4 mg / L.

Calculate:

A. The elimination half-life

B. The initial concentration

C. The apparent volume of distribution

D. The total body clearance

E. The Area Under the Curve

F. The percent amount eliminated after 12 hours.

Related Book For answer-question

Tax Research

ISBN: 9780136015314

4th edition

Authors: Barbara H. Karlin

Posted Date: Oct 18, 2020 06:17 AM

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The pk parameters for a drug given intravenously were described in the equation: D B = 1000

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a The Elimination halflife k0693t 12 0170693t12 t124076hrs b The initial concentration CCoe ket 144... View the full answer

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