The trailing edge of a migrating cell is the area of the cell farthest away from...

Transcribed Image Text:

The trailing edge of a migrating cell is the area of the cell farthest away from the direction of movement. What statement is TRUE about the trailing edge? The trailing edge is composed of many filopodia containing tight parallel bundles. These filopodia push the trailing edge away from the location it was previously occupying. The trailing edge is composed of stress fibers. Their contraction causes the trailing edge to pull away from the location it was previously occupying. What would happen to a migrating cell if an adaptor protein of a focal adhesion (such as talin or vinculin) was mutated/blocked? Actin microfilaments would cease polymerization, and the migrating cell would effectively cease all movement O The leading edge of the cell would fail to protrude, and there would be a retrograde flow of growing actin filaments away from the leading edge O The migrating cell would fail to bind extracellular matrix, and would effectively lose the directionality of its migration O The migrating cell would fail to bind to adjacent cells, and would effectively lose the directionality of its migration The trailing edge of a migrating cell is the area of the cell farthest away from the direction of movement. What statement is TRUE about the trailing edge? The trailing edge is composed of many filopodia containing tight parallel bundles. These filopodia push the trailing edge away from the location it was previously occupying. The trailing edge is composed of stress fibers. Their contraction causes the trailing edge to pull away from the location it was previously occupying. What would happen to a migrating cell if an adaptor protein of a focal adhesion (such as talin or vinculin) was mutated/blocked? Actin microfilaments would cease polymerization, and the migrating cell would effectively cease all movement O The leading edge of the cell would fail to protrude, and there would be a retrograde flow of growing actin filaments away from the leading edge O The migrating cell would fail to bind extracellular matrix, and would effectively lose the directionality of its migration O The migrating cell would fail to bind to adjacent cells, and would effectively lose the directionality of its migration