Question: This is the only information given, so please stop asking for more info. 2. Researchers were interested in a human syndrome characterized by short stature,
This is the only information given, so please stop asking for more info. 
2. Researchers were interested in a human syndrome characterized by short stature, hearing loss, premature aging and photosensitivity. Panel A shows the effect of UV on fibroblast survival. Panel B shows the effect of UV on lymphoblast replication. Panel C shows the effect of UV dose on unscheduled DNA synthesis (UDS), which is DNA synthesis that occurs at times other than S-phase. Ignore panel D. Based on these results, generate a possible hypothesis the molecular cause of this syndrome. Name one protein that could be involved and design experiment to test its involvement. Be sure to include appropriate controls. B 100 WT P3 0.8 10 0.6 % Survival relative to unirradiated > Population doublings in 72 h relative to unirradiated 0.4 X WT (L7) 0.2 L5 --L6 0 0 2 0.1 o 0 N 4 10 12 14 10 12 6 8 UV dose (J/m2 4 6 8 UV dose (J/m2) 140 120 WT P2 WI 100 P3 CS 80 UDS/cell (AU) 10000 9000 8000 7000 6000 5000 4000 3000 2000 1000 0 0 P2 P3 % RRS relative to unirradiated 0 60 40 20 0 2 10 12 0 5 15 20 4 6 8 UV dose (J/m) 10 UV dose (J/m)
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