To obtain the best separation of two weak acids in capillary electrophoresis, it makes sense to...

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To obtain the best separation of two weak acids in capillary electrophoresis, it makes sense to use the pH at which their charge difference is greatest. Prepare a spreadsheet to examine the charges of malonic acid and phthalic acid as a function of pH. At what pH is the difference greatest? The acid dissociation constants for malonic acid are K1 = 1.43 x 10-3 and K2 = 2.01 x 10-6. The acid dissociation constants for phthalic acid are K1 = 1.12 x 10-3 and K, = 3.90 x 10-6. pH = To obtain the best separation of two weak acids in capillary electrophoresis, it makes sense to use the pH at which their charge difference is greatest. Prepare a spreadsheet to examine the charges of malonic acid and phthalic acid as a function of pH. At what pH is the difference greatest? The acid dissociation constants for malonic acid are K1 = 1.43 x 10-3 and K2 = 2.01 x 10-6. The acid dissociation constants for phthalic acid are K1 = 1.12 x 10-3 and K, = 3.90 x 10-6. pH =