Total plasma volume is important in determining the required plasma component in blood replacement therapy for a person undergoing surgery. Plasma volume is influenced by the overall health and physical activity of an individual. Suppose that a random sample of42male firefighters are tested and that they have a plasma volume sample mean ofx= 37.5 ml/kg(milliliters plasma per kilogram body weight). Assume that=7.40ml/kgfor the distribution of blood plasma.

Find a 99% confidence interval for the population mean blood plasma volume in male firefighters. What is the margin of error? (Round your answers to two decimal places.)

lower limit

upper limit

margin of error

What conditions are necessary for your calculations? (Select all that apply.)

the distribution of weights is uniform

is unknown

the distribution of weights is normal

is known

nis large

Find the sample size necessary for a 99% confidence level with maximal margin of errorE=2.60for the mean plasma volume in male firefighters. (Round up to the nearest whole number.)